RAD52 Products

Antibodies
RAD52 Antibody
RAD52 Antibody
NBP1-61726
Species: Hu, Mu, Mk
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
RAD52 Antibody (5H9)
RAD52 Antibody (5H9)
NBP1-41208
Species: Hu
Applications: WB
Host: Mouse Monoclonal
RNAi
RAD52 RNAi
RAD52 RNAi
H00005893-R03
Species: Hu
RAD52 RNAi
RAD52 RNAi
H00005893-R02
Species: Hu
RAD52 RNAi
RAD52 RNAi
H00005893-R01
Species: Hu

Description

DNA double-strand breaks are generated by ionizing radiation and endogenously produced radicals, and they often are repaired through the RAD52 homologous recombination pathway. The RAD52 family includes RAD51, RAD52, RAD54, RAD54B and MRE11 genes. Rad51 and Rad52 proteins perform the key steps in homologous recombination (HR), including the search for DNA homology and strand exchange, through similar mechanisms. Mre11 functions in both non-homologous end joining, and meiotic HR, and it is essential in mitosis for chromosome maintenance. Rad54 belongs to the SWI2/SNF2 subfamily of ATPases, which includes the DNA helicases involved in replication, recombination, and repair, as it contains seven amino acid sequence motifs that are largely conserved. Rad54 ATPase activity is dependent on double-stranded (ds) DNA, and the ATPase activity of Rad54 is not absolutely required for its DNA repair function, suggesting that these activities occur at distinct regions of the molecule. RAD54B is significantly homologous to the RAD54 recombination gene. Expression of RAD54B is highest in testis and spleen, which are active in both meiotic and mitotic recombination.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Product By Gene ID 5893
Alternate Names
  • rhabdomyosarcoma antigen MU-RMS-40.23
  • recombination protein RAD52
  • DNA repair protein RAD52 homolog
  • RAD52 (S. cerevisiae) homolog
  • RAD52 homolog (S. cerevisiae)

Research Areas for RAD52

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
DNA Repair
Homologous Recombination

Bioinformatics Tool for RAD52

Discover related pathways, diseases and genes to RAD52. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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