Pyruvate Dehydrogenase Phosphatase/PDP1/PPM2C Products

Antibodies
Pyruvate Dehydrogenase Phosph ...
Pyruvate Dehydrogenase Phosphatase...
NBP1-82432
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Pyruvate Dehydrogenase Phosph ...
Pyruvate Dehydrogenase Phosphatase...
NBP1-87308
Species: Hu, Mu, Rt, Mouse, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Pyruvate Dehydrogenase Phosph ...
Pyruvate Dehydrogenase Phosphatase...
AF7260
Species: Hu
Applications: WB
Host: Sheep Polyclonal
Lysates
Proteins
Pyruvate Dehydrogenase Phosph ...
Pyruvate Dehydrogenase Phosphatase...
NBP1-87309PEP
Species: Hu
Applications: AC
Pyruvate Dehydrogenase Phosph ...
Pyruvate Dehydrogenase Phosphatase...
NBP1-87308PEP
Species: Hu
Applications: AC
Pyruvate Dehydrogenase Phosph ...
Pyruvate Dehydrogenase Phosphatase...
NBP1-82432PEP
Species: Hu
Applications: AC
RNAi

Description

Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.(provided by RefSeq)

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 54704
Alternate Names
  • EC 3.1.3.43
  • EC 3.1.3
  • PDPC 1
  • Protein phosphatase 2C
  • PDP 1
  • pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase
  • Pyruvate dehydrogenase phosphatase catalytic subunit 1
  • [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial
  • protein phosphatase 2C, magnesium-dependent, catalytic subunit
  • MGC119646
  • PDH
  • PPM2CFLJ56179
  • PDPFLJ32517
  • PDPC
  • pyruvate dehyrogenase phosphatase catalytic subunit 1

PTMs for Pyruvate Dehydrogenase Phosphatase/PDP1/PPM2C

Learn more about PTMs related to Pyruvate Dehydrogenase Phosphatase/PDP1/PPM2C.

Phosphorylation
Dephosphorylation
Oxidation
Acetylation
Methylation
Decarboxylation
Prenylation

Bioinformatics Tool for Pyruvate Dehydrogenase Phosphatase/PDP1/PPM2C

Discover related pathways, diseases and genes to Pyruvate Dehydrogenase Phosphatase/PDP1/PPM2C. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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