PSTPIP1 Products

Description

The protein encoded by the PSTPIP1 gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. (provided by RefSeq)

Bioinformatics

Entrez	9051 Human
Uniprot	AAH08602 Human NM_003978 Human NP_003969 Human
Product By Gene ID	9051
Alternate Names	CD2BP1CD2-binding protein 1 CD2BP1L CD2BP1S H-PIPPEST phosphatase-interacting protein 1 PAPASCD2 antigen-binding protein 1 proline-serine-threonine phosphatase interacting protein 1 proline-serine-threonine phosphatase-interacting protein 1 PSTPIPCD2 cytoplasmic tail-binding protein