PRR7 Products

Description

PRR7/TRAP3 (proline-rich 7, transmembrane adaptor protein 3) is a 28 kDa transmembrane adaptor protein ubiquitously expressed at low level (most in brain). Its amino acid sequence is extremely conserved among mammalian and other species. PRR7/TRAP3 contains potential palmitoylation motif and is found in lipid rafts. It is a part of the complex postsynaptic density fraction in neurons and associates with PSD-95, NMDA receptor and probably other proteins. The intracellular domain of PRR7/TRAP3 contains several tyrosines, a proline-rich sequence, and a C-terminal PDZ-binding motif. So far nothing is known about function of this protein. It may be involved in regulation of some receptor signaling and in formation of neurologic and immunologic synapse.

Bioinformatics

Entrez	80758 Human
Uniprot	NP_085044.2 Human
Product By Gene ID	80758
Alternate Names	proline-rich protein 7 Synaptic proline-rich membrane protein MGC10772 proline rich 7 (synaptic)

Diseases related to PRR7

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Cardiac Arrhythmia
Exhaustion
Blind Vision
Physiological Stress

Pathways for PRR7

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Circadian Rhythm
Photomorphogenesis
De-etiolation
Synapse Maturation
Tricarboxylic Acid Cycle
Lateral Root Formation
Shade Avoidance
Proteolysis
Photoperiodism
Hypersensitivity
Mrna Splicing
Response To Red Light
Response To Cold
Mrna Processing
Cold Acclimation

PTMs for PRR7

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Phosphorylation
Cleavage

Bioinformatics Tool for PRR7

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