Prokineticin R2/PROKR2 Products

Description

Corticotropin Releasing Factor Receptor 2 (CRHR2) expression has been reported in various regions of the brain, as well as in placenta, umbilical vein, heart, epididymis, gastrointestinal tract, adrenal, and skeletal muscle. It shows high-affinity CRF binding and also binds to urocortin I, II and III. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. CRCH2 alpha is the dominant isoform and is expressed widely. CRCH2 beta is expressed in the hippocampus, septum, amygdala, heart, and skeletal muscle. CRHR2 gamma is brain-specific. ESTs have been isolated from brain libraries.

Bioinformatics

Entrez	128674 Human 192649 Rat
Uniprot	NP_658986.1 Human
Product By Gene ID	128674
Alternate Names	dJ680N4.3 G protein-coupled receptor 73-like 1 GPR73bG-protein coupled receptor 73-like 1 GPR73L1Kallmann syndrome 3 (autosomal dominant) GPRg2KAL3 PKR2PK-R2 prokineticin receptor 2

Research Areas for Prokineticin R2/PROKR2

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Protein Phosphatase