PRDM16/MEL1 Products

Antibodies
PRDM16/MEL1 Antibody [Unconju ...
PRDM16/MEL1 Antibody [Unconjugated]
AF6295
Species: Hu, Mu
Applications: WB, IHC
Host: Sheep Polyclonal
PRDM16/MEL1 Antibody
PRDM16/MEL1 Antibody
NBP1-77096
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PRDM16/MEL1 Antibody
PRDM16/MEL1 Antibody
NBP1-71992
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC-P
Host: Rabbit Polyclonal
Proteins
PRDM16/MEL1 Recombinant Prote ...
PRDM16/MEL1 Recombinant Protein An...
NBP2-58350PEP
Species: Hu
Applications: AC
PRDM16/MEL1 Recombinant Prote ...
PRDM16/MEL1 Recombinant Protein An...
NBP2-56472PEP
Species: Hu
Applications: AC
PRDM16/MEL1 Blocking Peptide
PRDM16/MEL1 Blocking Peptide
NBP1-77096PEP
Species: Hu
Applications: AC
RNAi
PRDM16/MEL1 RNAi
PRDM16/MEL1 RNAi
H00063976-R01
Species: Hu
Applications: RNAi, RNAi SP
PRDM16/MEL1 RNAi
PRDM16/MEL1 RNAi
H00063976-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 63976
Alternate Names
  • PR domain-containing protein 16
  • PR domain zinc finger protein 16
  • MDS1/EVI1-like gene 1
  • Transcription factor MEL1
  • MEL1KIAA1675PFM13MGC166915
  • PR domain containing 16

Research Areas for PRDM16/MEL1

Find related products by research area and learn more about each of the different research areas below.

Chromatin Research

PTMs for PRDM16/MEL1

Learn more about PTMs related to PRDM16/MEL1.

Methylation
Oxidation
Phosphorylation
Sumoylation
Deacetylation
Acetylation

Bioinformatics Tool for PRDM16/MEL1

Discover related pathways, diseases and genes to PRDM16/MEL1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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