PPM1E Products

Antibodies
PPM1E Antibody
PPM1E Antibody
NBP1-86649
Species: Hu, Mouse, Rat
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PPM1E Antibody
PPM1E Antibody
NBP1-86650
Species: Hu, Mouse, Rat
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Proteins
PPM1E Recombinant Protein Ant ...
PPM1E Recombinant Protein Antigen
NBP1-86649PEP
Species: Hu
Applications: AC
PPM1E Recombinant Protein Ant ...
PPM1E Recombinant Protein Antigen
NBP1-86650PEP
Species: Hu
Applications: AC
RNAi
PPM1E RNAi
PPM1E RNAi
H00022843-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

The protein encoded by the PPM1E gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase was identified as an interacting protein of Rho guanine nucleotide exchange factors (PIX). PIX proteins are regulators of p21/Cdc42/Rac1-activated kinase 1 (PAK1), a protein kinase mediating biological effects downstream of Rho GTPases. This phosphatase has been shown to block the effects of PAK, and thus inhibit actin stress fiber breakdown and morphological changes driven by cell division cycle 42 (CDC42). (provided by RefSeq)

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 22843
Alternate Names
  • partner of PIX 1
  • caMKN
  • CAMKN
  • partner of PIX-alpha
  • PP2CH
  • caMKP-nucleus
  • ca(2+)/calmodulin-dependent protein kinase phosphatase N
  • nuclear calmodulin-dependent protein kinase phosphatase
  • KIAA1072
  • partner of PIXA
  • DKFZp781F1422
  • protein phosphatase 1E
  • CaMKP-N
  • protein phosphatase 1E (PP2C domain containing)
  • POPX1
  • protein phosphatase, Mg2+/Mn2+ dependent, 1E

Pathways for PPM1E

View related products by pathway and learn more about each of the pathways below.

Translation
Gene Silencing
Aging
Histone Acetylation

Research Areas for PPM1E

Find related products by research area and learn more about each of the different research areas below.

Protein Phosphatase

PTMs for PPM1E

Learn more about PTMs related to PPM1E.

Phosphorylation
Dephosphorylation
Acetylation

Bioinformatics Tool for PPM1E

Discover related pathways, diseases and genes to PPM1E. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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