PPAP2A Products

Description

The protein encoded by the PPAP2A gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is an integral membrane glycoprotein, and has been shown to be a surface enzyme that plays an active role in the hydrolysis and uptake of lipids from extracellular space. The expression of this gene is found to be regulated by androgen in a prostatic adenocarcinoma cell line. At least two alternatively spliced transcript variants encoding distinct isoforms have been described. (provided by RefSeq)

Bioinformatics

Entrez	8611 Human
Uniprot	AAH39847 Human NM_003711 Human NP_003702.2 Human O14494-2 Human
Product By Gene ID	8611
Alternate Names	EC 3.1.3.4 lipid phosphate phosphohydrolase 1 lipid phosphate phosphohydrolase 1a LLP1a LPP1PAP2a2 PAP2 PAP2a PAP2-alpha PAP-2aPAP2alpha2 PAPalpha1 Phosphatidate phosphohydrolase type 2a Phosphatidic acid phosphatase 2a phosphatidic acid phosphatase type 2A phosphatidic acid phosphohydrolase type 2a type 2 phosphatidic acid phosphohydrolase type-2 phosphatidic acid phosphatase alpha

Research Areas for PPAP2A

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Cell Cycle and Replication