PP1 alpha/PPP1A Products

Antibodies
PP1 alpha/PPP1A Antibody (6D1 ...
PP1 alpha/PPP1A Antibody (6D1)
NBP1-51600
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
PP1 alpha/PPP1A Antibody
PP1 alpha/PPP1A Antibody
NBP2-38559
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PP1 alpha/PPP1A Antibody (490 ...
PP1 alpha/PPP1A Antibody (490314)
MAB6105
Species: Hu
Applications: WB
Host: Mouse Monoclonal
Lysates
PP1 alpha/PPP1A Overexpressio ...
PP1 alpha/PPP1A Overexpression Lys...
NBP2-10998
Applications: WB
PP1 alpha/PPP1A Overexpressio ...
PP1 alpha/PPP1A Overexpression Lys...
NBL1-14670
Applications: WB
Proteins
PP1 alpha/PPP1A Recombinant P ...
PP1 alpha/PPP1A Recombinant Protei...
NBP2-38559PEP
Species: Hu
Applications: AC
PP1 alpha/PPP1A Recombinant P ...
PP1 alpha/PPP1A Recombinant Protein
NBP1-72418
Species: Hu
Applications: PAGE
RNAi
PP1 alpha/PPP1A RNAi
PP1 alpha/PPP1A RNAi
H00005499-R05
Species: Hu
PP1 alpha/PPP1A RNAi
PP1 alpha/PPP1A RNAi
H00005499-R04
Species: Hu
PP1 alpha/PPP1A RNAi
PP1 alpha/PPP1A RNAi
H00005499-R06
Species: Hu

Description

Protein phosphatase 1 (PP1) is a major eukaryotic protein serine/threonine phosphatase that regulates an enormous variety of cellular functions through the interaction of its catalytic subunit (PP1c) with over fifty different established or putative regulatory subunits (1). The coordinated and reciprocal action of serine/threonine (Ser/Thr) protein kinases and phosphatases produces transient phosphorylation, a fundamental regulatory mechanism for many biological processes. PP1 is ubiquitously distributed and regulates a broad range of cellular functions, including glycogen metabolism, cell-cycle progression and muscle relaxation. PP1 has evolved effective catalytic machinery but lacks substrate specificity. Substrate specificity is conferred upon PP1 through interactions with a large number of regulatory subunits (2). It has been shown that PP1 determines the efficacy of learning and memory by limiting acquisition and favouring memory decline. When PP1 is genetically inhibited during learning, short intervals between training episodes are sufficient for optimal performance (3).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 5499
Alternate Names
  • serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  • protein phosphatase 1, catalytic subunit, alpha isoform
  • serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit
  • PP1alpha
  • PPP1AMGC1674
  • PP-1AMGC15877
  • EC 3.1.3.16
  • protein phosphatase 1, catalytic subunit, alpha isozyme

Research Areas for PP1 alpha/PPP1A

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Protein Phosphatase

PTMs for PP1 alpha/PPP1A

Learn more about PTMs related to PP1 alpha/PPP1A.

Phosphorylation
Dephosphorylation

Bioinformatics Tool for PP1 alpha/PPP1A

Discover related pathways, diseases and genes to PP1 alpha/PPP1A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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