PLK1 Products

Antibodies
PLK1 Antibody
PLK1 Antibody
NB100-56651
Species: Hu, Mu, Rt, Po, Bv, Ca, Pm, C. elegans, Xenopus, Zebrafish
Applications: WB, IHC-P
Host: Rabbit Polyclonal
PLK1 Antibody
PLK1 Antibody
Species: Hu, Primate, Rabbit
Applications: WB, ICC/IF, IP, PLA
Host: Rabbit Polyclonal
PLK1 Antibody (2G12)
PLK1 Antibody (2G12)
H00005347-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP, PLA
Host: Mouse Monoclonal
Antibody Pairs
PLK1 Antibody Pair
PLK1 Antibody Pair
H00005347-PW2
Species: Hu
Applications: WB, IP
PLK1 Antibody Pair
PLK1 Antibody Pair
H00005347-PW1
Species: Hu
Applications: WB, IP
Lysates
PLK1 Overexpression Lysate (N ...
PLK1 Overexpression Lysate (Native)
NBL1-14515
Applications: WB
PLK1 Overexpression Lysate (D ...
PLK1 Overexpression Lysate (Denatu...
H00005347-T01
Applications: WB
Proteins
PLK1 Recombinant Protein Anti ...
PLK1 Recombinant Protein Antigen
NBP2-49014PEP
Species: Hu
Applications: AC
PLK1 Recombinant Protein Anti ...
PLK1 Recombinant Protein Antigen
NBP2-49074PEP
Species: Hu
Applications: AC
PLK1 Recombinant Protein
PLK1 Recombinant Protein
P4765
Species: Hu
Applications: Func, PAGE
RNAi
PLK1 RNAi
PLK1 RNAi
H00005347-R02
Species: Hu

Description

Considerable evidence indicates that a Polo-Like Kinase (PLK) plays an important role in cell cycle regulation. PLK is also required for bipolar spindle formation, activation of the anaphase-promoting complex/cyclosome, and cytokinesis. Recent work led to the identification of a PLKK that is thought to be responsible for activation of PLK. Recent work (Erikson, et al., 2004) has shown that PLKK is in turn activated by phosphorylation at three sites (Ser482, Ser486 and Ser490). Thus activation of PLK is thought to involve a kinase cascade involving the phosphorylation of Ser482,486,490 in PLKK.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 5347
Alternate Names
  • EC 2.7.11
  • EC 2.7.11.21
  • serine/threonine-protein kinase PLK1
  • STPK13
  • polo like kinase
  • PLK-1
  • polo (Drosophia)-like kinase
  • PLK
  • cell cycle regulated protein kinase
  • Serine/threonine-protein kinase 13
  • polo-like kinase 1polo-like kinase (Drosophila)

Research Areas for PLK1

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
Cell Cycle and Replication
Checkpoint signaling
Core ESC-Like Genes
DNA Double Strand Break Repair
DNA Repair
Mitotic Regulators
Phospho-Specific
Stem Cell Markers

Bioinformatics Tool for PLK1

Discover related pathways, diseases and genes to PLK1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.