Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Mu
Applications: Bioactivity
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Secretory phospholipases A2 (PLA2s) have been purified from a variety of mammalian tissues as well as from insect and snake venoms. The prototype group I PLA2, the pancreatic PLA2 (PLA2G1B; MIM 172410), is involved in digestion, smooth muscle contraction, and cell proliferation. The prototype group II PLA2, the inflammatory-type PLA2 (PLA2G2A; MIM 172411), is involved in inflammatory conditions and is upregulated by proinflammatory cytokines like tumor necrosis factor (TNF; MIM 191160) and interleukin-1 (e.g., IL1B; MIM 147720). Differential toxicity of snake venom Pla2 appears to be linked to a variety of high-affinity receptors in different organs (Ancian et al., 1995 (PubMed 7721806)).(supplied by OMIM)
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
22925 |
| Alternate Names |
- 180 kDa secretory phospholipase A2 receptor
- CLEC13CC-type lectin domain family 13 member C
- phospholipase A2 receptor 1, 180kDa
- PLA2G1R
- PLA2IR
- PLA2-RM-type receptor
- PLA2Rphospholipase A2 receptor 1, 180kD
- secretory phospholipase A2 receptor
|
