PKC iota Products

Antibodies
PKC iota Antibody
PKC iota Antibody
NBP1-84959
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PKC iota Antibody (1G11)
PKC iota Antibody (1G11)
H00005584-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, RNAi
Host: Mouse Monoclonal
PKC iota Antibody
PKC iota Antibody
NBP1-32413
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
PKC iota Overexpression Lysat ...
PKC iota Overexpression Lysate (Na...
NBL1-14777
Applications: WB
Proteins
PKC iota Recombinant Protein ...
PKC iota Recombinant Protein Antigen
NBP1-84959PEP
Species: Hu
Applications: AC
PKC iota Recombinant Protein ...
PKC iota Recombinant Protein Antigen
NBP2-58629PEP
Species: Hu
Applications: AC
Recombinant Human PKC iota Pr ...
Recombinant Human PKC iota Protein
P4189
Species: Hu
Applications: Func, PAGE
RNAi
PKC iota RNAi
PKC iota RNAi
H00005584-R01V
Species: Hu
Applications: WB, RNAi, RNAi SP
PKC iota RNAi
PKC iota RNAi
H00005584-R04
Species: Hu
Applications: RNAi, RNAi SP

Description

PKC iota encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 5584
Alternate Names
  • aPKC-lambda/iota
  • EC 2.7.11
  • PRKC-lambda/iota
  • protein kinase C iota type
  • DXS1179E
  • MGC26534
  • Atypical protein kinase C-lambda/iota
  • EC 2.7.11.13
  • PKCI
  • nPKC-iota
  • protein kinase C, iota

Research Areas for PKC iota

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Protein Kinase
Signal Transduction

PTMs for PKC iota

Learn more about PTMs related to PKC iota.

Phosphorylation

Bioinformatics Tool for PKC iota

Discover related pathways, diseases and genes to PKC iota. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.