PKC delta Products

Antibodies
PKC delta Antibody
PKC delta Antibody
NB100-82142
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PKC delta Antibody
PKC delta Antibody
AF4585
Species: Hu
Applications: WB
Host: Sheep Polyclonal
PKC delta Antibody
PKC delta Antibody
NBP1-90351
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
PKC delta Overexpression Lysa ...
PKC delta Overexpression Lysate (D...
H00005580-T01
Species: Hu
Applications: WB
PKC delta Overexpression Lysa ...
PKC delta Overexpression Lysate (N...
NBP2-10423
Applications: WB
PKC delta Overexpression Lysa ...
PKC delta Overexpression Lysate (N...
NBL1-14771
Applications: WB
Proteins
PKC delta Recombinant Protein ...
PKC delta Recombinant Protein Antigen
NBP1-90351PEP
Species: Hu
Applications: AC
PKC delta Recombinant Protein ...
PKC delta Recombinant Protein Antigen
NBP1-90957PEP
Species: Hu
Applications: AC
PKC delta Recombinant Protein ...
PKC delta Recombinant Protein
P4222
Species: Hu
Applications: Func, PAGE
RNAi
PKC delta RNAi
PKC delta RNAi
H00005580-R01V
Species: Hu
Applications: WB, RNAi SP
PKC delta RNAi
PKC delta RNAi
H00005580-R08
Species: Hu
PKC delta RNAi
PKC delta RNAi
H00005580-R07
Species: Hu

Description

PKC-delta has a biological activity which is closely related to Pkc1, and PKC-delta activates the Pkc1-mediated pathway through an activation of the Bck1 kinase. PKC-delta appears to play a critical role in growth control of yeast and mammalian cells. Suppression experiments suggest that PKC-delta desensitizes the pathway by regulating an aspect of G protein function (1). PKC-delta phosphorylates hRad9 in vitro and in cells exposed to genotoxic agents. It has been shown that PKC-delta is required for binding of hRad9 to Bcl-2. In concert with these results, inhibition of PKC-delta attenuates Rad9-mediated apoptosis. These findings demonstrate that PKC-delta is responsible for the regulation of Rad9 in the Hus1-Rad1 complex and in the apoptotic response to DNA damage (2). It has been reported a mechanism for the regulation of peripheral B-cell survival by serine/threonine protein kinase Cdelta (PKC-delta): spontaneous death of resting B cells is regulated by nuclear localization of PKC-delta that contributes to phosphorylation of histone H2B at serine 14 (S14-H2B) (3).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Mouse
Rat
Product By Gene ID 5580
Alternate Names
  • MGC49908
  • EC 2.7.11
  • MAY1
  • protein kinase C delta VIII
  • EC 2.7.11.13
  • protein kinase C delta type
  • nPKC-delta
  • PKCD
  • protein kinase C, delta

Research Areas for PKC delta

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Protein Kinase
Signal Transduction

Bioinformatics Tool for PKC delta

Discover related pathways, diseases and genes to PKC delta. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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