PIMT Products

Antibodies
PIMT Antibody
PIMT Antibody
NBP1-92271
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PIMT Antibody
PIMT Antibody
NB100-2595
Species: Hu
Applications: WB, IHC, IHC-P, IP
Host: Rabbit Polyclonal
PIMT Antibody
PIMT Antibody
NBP2-44294
Species: Hu, Feline, Ferret, Primate, Rabbit, Rat
Applications: WB, IP
Host: Rabbit Polyclonal
Proteins
PIMT Recombinant Protein
PIMT Recombinant Protein
H00096764-P01
Species: Hu
Applications: WB, ELISA, PA
PIMT Recombinant Protein Anti ...
PIMT Recombinant Protein Antigen
NBP1-92271PEP
Species: Hu
Applications: AC
RNAi
PIMT RNAi
PIMT RNAi
H00096764-R01
Species: Hu

Description

Nuclear receptor coactivators participate in the transcriptional activation of specific genes by nuclear receptors. A new nuclear receptor coactivator-interacting protein, designated PIMT, was identified from a human liver cDNA library by using the coactivator peroxisome proliferator-activated receptor-interacting protein (PRIP) as bait in a yeast 2-hybrid screen. The PIMT cDNA encodes an 852-amino acid protein containing a 9-amino acid methyltransferase motif I (VVDAFCGVG) and an invariant segment (GXXGXXI) found in K-homology motifs of many RNA-binding proteins. Northern blot analysis demonstrated ubiquitous expression of a 3.2-kb PIMT transcript, with highest expression in heart, skeletal muscle, kidney, liver, and placenta. Immunofluorescence studies showed that the PIMT and PRIP proteins are colocalized in the nucleus. PIMT binds 5-adenosyl-L-methionine, the methyl donor for the methyltransfer reaction, and it also binds RNA, suggesting that it is an RNA methyltransferase.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 96764
Alternate Names
  • trimethylguanosine synthase homolog (S. cerevisiae)
  • EC 2.1.1
  • PRIP-interacting protein with methyltransferase motif
  • HCA137
  • CLL-associated antigen KW-2
  • EC 2.1.1.-
  • PIPMT
  • trimethylguanosine synthase homolog
  • Nuclear receptor coactivator 6-interacting protein
  • trimethylguanosine synthase
  • Hepatocellular carcinoma-associated antigen 137
  • PRIP-interacting protein with methyltransferase domain
  • Cap-specific guanine-N2 methyltransferase
  • PRIP-interacting protein PIPMT
  • nuclear receptor coactivator 6 interacting protein
  • NCOA6IPSEREX-defined
  • PIMTFLJ22995
  • DKFZp762A163
  • trimethylguanosine synthase 1

Research Areas for PIMT

Find related products by research area and learn more about each of the different research areas below.

Transcription Factors and Regulators

PTMs for PIMT

Learn more about PTMs related to PIMT.

Methylation
Phosphorylation
Cleavage

Bioinformatics Tool for PIMT

Discover related pathways, diseases and genes to PIMT. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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