PHKG2 Products

Description

PHKG2, also known as Phosphorylase b kinase gamma catalytic chain, liver/testis isoform, has 2 isoforms, a 406 amino acid long isoform that is 46 kDa and a short 374 amino acid isoform that is 43 kDa, as catalytic subunit of the phosphorylase b kinase (PHK) mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase and may regulate glycogeneolysis in the testis and phosphorylates PYGM in vitro. Studies on this protein have shown a relationship with the following diseases and disorders: glycogen storage disease, cirrhosis due to liver, phosphorylase kinase deficiency, hepatitis, metabolic disorders, hypotonia malaria, and alcoholism. This protein has interactions with PHKG1, UBE3A, PHKA2, PHKB, and PYGL in PKA signaling, cAMP Pathway, activation of cAMP-dependent PKA, alpha-adrenergic signaling, metabolism of carbohydrates, glycogen breakdown (glycogenolysis), glucose metabolism, calcium signaling pathway and insulin signaling pathway.

Bioinformatics

Uniprot	AAH02541 Human AAH02541.1 Human NM_000294 Human NP_000285 Human NP_000285.1 Human P15735 Human
Product By Gene ID	5261
Alternate Names	EC 2.7.11 EC 2.7.11.19 GSD9C PHK-gamma-T phosphorylase b kinase gamma catalytic chain, testis/liver isoform Phosphorylase kinase subunit gamma-2 phosphorylase kinase, gamma 2 (testis) Phosphorylase kinase, gamma 2 (testis/liver) PSK-C3

Research Areas for PHKG2

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Protein Kinase