PF1 Products

Description

PHD factor 1 (PF1) was identified as a protein that interacts with mSin3A-histone deacetylase corepressor, a multiprotein complex that mediates transcriptional repression. PF1 is a plant homeodomain zinc finger protein that also bears a forkhead-associated (FHA) domain. PF1 appears to facilitate the recruitment of the mSin3A complex to DNA for transcriptional repression. It has also been shown to interact with the histone deacetylase containing corepressor transducin-like enhancer of split (TLE) and may play a role in bridging the mSin3A and TLE transcriptional networks. Alternate names for PF1 include PHF12, PHD finger protein 12, and KIAA1523.

Bioinformatics

Uniprot	NP_001028733 Human NP_001028733.1 Human Q96QT6 Human
Product By Gene ID	57649
Alternate Names	FLJ34122 KIAA1523MGC131914 PF1 Pf1 PHD factor 1 PHD finger protein 12 PHD zinc finger transcription factor