PEX19 Products

Description

PEX19 is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS). [provided by RefSeq]

Bioinformatics

Uniprot	AAH00496 Human AAH00496.1 Human NM_002857 Human NP_002848 Human NP_002848.1 Human P40855 Human PXF_HUMAN Human Q8VCI5 Mouse
Product By Gene ID	5824
Alternate Names	D1S2223Ehousekeeping gene, 33kD HK3333 kDa housekeeping protein Peroxin-19 peroxisomal biogenesis factor 19 Peroxisomal farnesylated proteinFLJ55296 PMP1 PMPI PXFperoxin-19 PXMP1

Diseases related to PEX19

Discover more about diseases related to PEX19.

Peroxisomal Disorders
Zellweger Syndrome
Disorders Of Peroxisome Biogenesis
Adrenoleukodystrophy
Comatose
Muscle Hypotonia
Major Depressive Disorder
Depressive Disorder
Chondrodysplasia Punctata
Inborn Errors Of Metabolism
Metabolic Acidosis
Neuronal Migration Disorders
Refsum Disease
Osteosarcoma
Malignant Neoplasms
Neoplasms
Innate Immune Response
Unconjugated Hyperbilirubinemia
Asthma

Pathways for PEX19

View related products by pathway and learn more about each of the pathways below.

Protein Import
Localization
Membrane Biogenesis
Transport
Membrane Assembly
Translation
Membrane Fission
Peroxisome Inheritance
Peroxisome Membrane Biogenesis
Prenylation
Glycolysis
Protein Targeting
Fertilization
Aging
Proteolysis
Embryo Development
Flocculation
Prophase
Seed Germination
Peroxisome Fission

PTMs for PEX19

Learn more about PTMs related to PEX19.

Farnesylation
Prenylation
Demethylation

Bioinformatics Tool for PEX19

Discover related pathways, diseases and genes to PEX19. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.