WB, Simple Western, ICC/IF, IHC-PHost:
Hu, Mu, Po, Bv, Pm, ShApplications:
WB, Simple Western, IHC, IHC-PHost:
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
Adipocyte differentiation-related protein (ADFP), also known as Adipophilin and Perilipin 2, is a major constituent of the globule surface membrane. ADFP is required for the development and maintenance of adipose tissue, and an increase in ADFP mRNA levels is one of the earliest indications of adipocyte differentiation.
ADFP is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells. In tissues, however, expression of adipophilin is restricted to specific cell types, such as lactating mammary epithelial cells, adrenal cortex cells, Sertoli and Leydig cells of the male reproductive system, and steatosis or fatty change hepatocytes in alcoholic liver cirrhosis.
ADFP antibodies may be useful as a new marker for the identification of specialized differentiated cells containing lipid droplets and for diseases associated with fat-accumulating cells.
Bioinformatics Tool for Perilipin-2/ADFP
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Related Perilipin-2/ADFP Blog Posts
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|The affects of Perilipin 2 on diet and metabolism
Perilipin 2 belongs to the Perilipin family, which consists of proteins that coat intracellular lipid storage droplets. Perilipin 2 in particular is involved in lipid globule surface membrane composition, and has also been implicated in the develo... Read more.