Perforin Products

Antibodies
Antibody Pairs
Perforin Antibody Pair
Perforin Antibody Pair
H00005551-PW2
Species: Hu
Applications: WB, IP
Perforin Antibody Pair
Perforin Antibody Pair
H00005551-PW1
Species: Hu
Applications: WB, IP
Lysates
Perforin Overexpression Lysat ...
Perforin Overexpression Lysate (De...
H00005551-T01
Species: Hu
Applications: WB
Perforin Overexpression Lysat ...
Perforin Overexpression Lysate (Na...
NBL1-14750
Applications: WB
Perforin Overexpression Lysat ...
Perforin Overexpression Lysate (Na...
NBP2-10656
Applications: WB
Proteins
Perforin Recombinant Protein
Perforin Recombinant Protein
H00005551-P01
Species: Hu
Applications: WB, ELISA, PA
Perforin Partial Recombinant ...
Perforin Partial Recombinant Protein
H00005551-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
Perforin RNAi
Perforin RNAi
H00005551-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Perforin (PRF1) is a 70 kD cytolytic protein that is the major protein constituent of cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Specifically, perforin enters the target cell's plasma membrand and creates a intercellular pore to mediate targeted cell lysis. PRF1 antibodies are useful tools for lysis research on both CTLs and NK cells.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Human
Rat
Product By Gene ID 5551
Alternate Names
  • HPLH2
  • MGC65093
  • Cytolysin
  • FLH2
  • perforin-1
  • Lymphocyte pore-forming protein
  • HPLH2lymphocyte pore forming protein
  • PFPcytolysin
  • P1PFN1
  • perforin 1 (pore forming protein)

Research Areas for Perforin

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Apoptosis
Immunology

Bioinformatics Tool for Perforin

Discover related pathways, diseases and genes to Perforin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Perforin Blog Posts

Check out the latest blog posts on Perforin.
Perforin a Protective Serial Killer
Secretory granule-mediated cell death is one of the the key mechanisms for elimination of virus-infected and transformed target cells by cytotoxic lymphocytes. Formation of the immunological synapse between an effector and a target cell leads to exocy...    Read more.
Perforin Antibodies Reveal Links to Apoptosis and Immune Response
Perforin, also known as the pore-forming protein, pfp, is a 70 kD cytolytic protein expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. It is one of the major effector molecules used by CTL and NK cel...    Read more.
Perforin Antibodies for Detecting Immune System Diseases
¬†Perforin is a calcium-dependent pore forming cytolytic protein. Perforin is partially homologous to the terminal components of the membrane attack complex of complement and produces pores of up to 20nm in diameter on target membranes. Killer lymphocy...    Read more.
Perforin Antibodies Reveal Links to Apoptosis and Immune Response
Perforin, also known as the pore-forming protein, pfp, is a 70 kD cytolytic protein expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. It is one of the major effector molecules used by CTL and NK cel...    Read more.
Read more Perforin related blogs.