PDZK1 Products

Antibodies
PDZK1 Antibody
PDZK1 Antibody
NB400-149
Species: Hu, Mu, Bv, Rt(-)
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PDZK1 Antibody
PDZK1 Antibody
NBP1-82572
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PDZK1 Antibody [Unconjugated] ...
PDZK1 Antibody [Unconjugated]
AF4997
Species: Hu, Mu
Applications: WB, IHC
Host: Sheep Polyclonal
Lysates
PDZK1 Overexpression Lysate ( ...
PDZK1 Overexpression Lysate (Native)
NBP2-04231
Applications: WB
Proteins
PDZK1 Recombinant Protein Ant ...
PDZK1 Recombinant Protein Antigen
NBP1-82573PEP
Species: Hu
Applications: AC
PDZK1 Recombinant Protein Ant ...
PDZK1 Recombinant Protein Antigen
NBP1-82572PEP
Species: Hu
Applications: AC
Recombinant Human PDZK1 Prote ...
Recombinant Human PDZK1 Protein
NBP2-23318
Species: Hu
Applications: PAGE
RNAi
PDZK1 RNAi
PDZK1 RNAi
H00005174-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

PDZK1 is a scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. It may be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, PDZK1 may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. It may also play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. PDZK1 may potentiate the CFTR chloride channel activity. PDZK1 functions to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism and may be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport, therefore playing an important role in tubule function.

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 5174
Alternate Names
  • PDZ domain-containing protein 1
  • CFTR-associated protein of 70 kDa
  • Na(+)/H(+) exchanger regulatory factor 3
  • NHERF-3
  • NaPi-Cap1
  • CAP70
  • PDZ-containing kidney protein 1
  • Sodium-hydrogen exchanger regulatory factor 3
  • naPi-Cap1
  • Na/Pi cotransporter C-terminal-associated protein 1
  • NHERF3PDZD1Na(+)/H(+) exchange regulatory cofactor NHE-RF3
  • CLAMP
  • PDZ domain containing 1

Research Areas for PDZK1

Find related products by research area and learn more about each of the different research areas below.

Cellular Markers
Diabetes Research
Endothelial Cell Markers
Growth and Development
Lipid and Metabolism
Neuronal Cell Markers
Plasma Membrane Markers
Signal Transduction

Bioinformatics Tool for PDZK1

Discover related pathways, diseases and genes to PDZK1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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