PCMT1 Products

Antibodies
PCMT1 Antibody
PCMT1 Antibody
NBP1-85806
Species: Hu, Mu, Rt, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PCMT1 Antibody (1D6)
PCMT1 Antibody (1D6)
H00005110-M02
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Mouse Monoclonal
PCMT1 Antibody
PCMT1 Antibody
NBP1-33019
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
PCMT1 Overexpression Lysate ( ...
PCMT1 Overexpression Lysate (Native)
NBL1-14181
Applications: WB
Proteins
PCMT1 Recombinant Protein Ant ...
PCMT1 Recombinant Protein Antigen
NBP1-85806PEP
Species: Hu
Applications: AC
PCMT1 Recombinant Protein
PCMT1 Recombinant Protein
NBP1-44464
Species: Hu
Applications: PAGE
RNAi
PCMT1 RNAi
PCMT1 RNAi
H00005110-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.[supplied by OMIM]

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Product By Gene ID 5110
Alternate Names
  • EC 2.1.1
  • EC 2.1.1.77
  • protein-L-isoaspartate(D-aspartate) O-methyltransferase
  • L-isoaspartyl protein carboxyl methyltransferase
  • L-isoaspartyl/D-aspartyl methyltransferase
  • PIMT
  • Protein-beta-aspartate methyltransferase
  • Protein L-isoaspartyl/D-aspartyl methyltransferase
  • protein-L-isoaspartate (D-aspartate) O-methyltransferase

PTMs for PCMT1

Learn more about PTMs related to PCMT1.

Methylation
Phosphorylation
Deamidation

Bioinformatics Tool for PCMT1

Discover related pathways, diseases and genes to PCMT1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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