PARP10 Products

Description

PARP10 is a member of the poly(ADP-ribose) polymerase (PARP) family involved in a variety of processes which includes DNA metabolism, the DNA damage response, transcription and the maintenance of genomic stability. Although each member of the PARP family exhibits poly(ADP-ribose) polymerase activity which catalyzes the attachment of ADP-ribose units from NAD+ to substrate proteins, the endogenous substrates of many of the family members, including PARP10, remain to be identified. Recent studies have shown that PARP10 is localized to the nucleoli and associates with RNA polymerase II. PARP10 is a substrate of and is activated by CDK2 and may serve an important function in cell proliferation. Alternate names for PARP10 include poly(ADP-ribose) polymerase 10, PARP-10, and FLJ14464.

Bioinformatics

Entrez	84875 Human
Uniprot	NP_116178.1 Human
Product By Gene ID	84875
Alternate Names	ARTD10 EC 2.4.2.30 FLJ14464 PARP10 PARP-10 poly (ADP-ribose) polymerase family, member 10 poly [ADP-ribose] polymerase 10

Research Areas for PARP10

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
DNA Repair
Hypoxia