PARL Products

Description

PARL encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Bioinformatics

Uniprot	NM_018622 Human NP_061092 Human NP_061092.3 Human Q9H300 Human
Product By Gene ID	55486
Alternate Names	EC 3.4.21.105 mitochondrial presenilin associated, rhomboid-like PRO2207 rhomboid 7 homolog 1

Research Areas for PARL

Find related products by research area and learn more about each of the different research areas below.

Alzheimers Research
Apoptosis
Mitochondrial Fusion Proteins
Neuroscience