PANK2 Products

Antibodies
PANK2 Antibody (3H9)
PANK2 Antibody (3H9)
Species: Hu, Rt, Ca, Pm
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
PANK2 Antibody
PANK2 Antibody
NBP1-88295
Species: Hu, Mouse, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
PANK2 Antibody (2B12)
PANK2 Antibody (2B12)
H00080025-M01
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
Lysates
PANK2 Overexpression Lysate ( ...
PANK2 Overexpression Lysate (Native)
NBP2-09917
Applications: WB
PANK2 Overexpression Lysate ( ...
PANK2 Overexpression Lysate (Native)
NBP2-10009
Applications: WB
PANK2 Overexpression Lysate ( ...
PANK2 Overexpression Lysate (Native)
NBL1-14091
Applications: WB
Proteins
PANK2 Recombinant Protein Ant ...
PANK2 Recombinant Protein Antigen
NBP1-88295PEP
Species: Hu
Applications: AC
RNAi
PANK2 RNAi
PANK2 RNAi
H00080025-R11
Species: Hu
Applications: RNAi, RNAi SP
PANK2 RNAi
PANK2 RNAi
H00080025-R08
Species: Hu
Applications: RNAi, RNAi SP
PANK2 RNAi
PANK2 RNAi
H00080025-R07
Species: Hu
Applications: RNAi, RNAi SP

Description

PANK2 encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 80025
Alternate Names
  • EC 2.7.1.33
  • pantothenate kinase 2, mitochondrial
  • hPanK2
  • Hallervorden-Spatz syndrome
  • C20orf48
  • MGC15053
  • Pantothenic acid kinase 2
  • FLJ17232
  • HSS
  • PKANneurodegeneration with brain iron accumulation 1 (Hallervorden-Spatz syndrome)
  • HARPFLJ11729
  • NBIA1
  • pantothenate kinase 2

PTMs for PANK2

Learn more about PTMs related to PANK2.

Phosphorylation
Oxidation
Cleavage

Bioinformatics Tool for PANK2

Discover related pathways, diseases and genes to PANK2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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