PAK1 Products

Antibodies
PAK1 Antibody (4D1)
PAK1 Antibody (4D1)
H00005058-M02
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP
Host: Mouse Monoclonal
PAK1 Antibody
PAK1 Antibody
NBP2-19680
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PAK1 Antibody
PAK1 Antibody
NBP1-85802
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
PAK1 Antibody Pair
PAK1 Antibody Pair
H00005058-PW1
Species: Hu
Applications: WB, IP
Lysates
PAK1 Overexpression Lysate (D ...
PAK1 Overexpression Lysate (Denatu...
H00005058-T01
Species: Hu
Applications: WB
PAK1 Overexpression Lysate (N ...
PAK1 Overexpression Lysate (Native)
NBP2-09482
Applications: WB
Proteins
PAK1 Recombinant Protein
PAK1 Recombinant Protein
H00005058-P01
Species: Hu
Applications: WB, ELISA, PA
PAK1 Partial Recombinant Prot ...
PAK1 Partial Recombinant Protein
H00005058-Q01
Species: Hu
Applications: WB, ELISA, PA
PAK1 Recombinant Protein Anti ...
PAK1 Recombinant Protein Antigen
NBP1-85802PEP
Species: Hu
Applications: AC
RNAi
PAK1 RNAi
PAK1 RNAi
H00005058-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

p21-activated kinase 1 (PAK1) is a member of a family of serine/threonine protein kinase defined by their interaction with the small GTPases, Cdc42 and Rac (1-2). The PAK proteins can be essentially divided into two categories, groups I (PAK1, PAK2 and PAK3) and group II (PAK4, PAK5 and PAK6), based on their structures (3). PAK1 participates in regulating the actin cytoskeleton, focal adhesion contacts, cell motility, apoptosis and transcription. It also promotes the disassembly of stress fibers (4-5). PAK1 also binds PIX (PAK-binding protein), COOL and adapter protein Nck (5).

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 5058
Alternate Names
  • MGC130000
  • EC 2.7.11
  • EC 2.7.11.1
  • Alpha-PAK
  • p65-PAK
  • STE20 homolog, yeast
  • p21-activated kinase 1
  • serine/threonine-protein kinase PAK 1
  • PAK-1
  • alpha-PAK
  • p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)
  • PAKalpha
  • p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
  • MGC130001
  • p21 protein (Cdc42/Rac)-activated kinase 1

Research Areas for PAK1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Breast Cancer
Cancer
Neuroscience
Phospho-Specific
Signal Transduction

Bioinformatics Tool for PAK1

Discover related pathways, diseases and genes to PAK1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related PAK1 Blog Posts

Check out the latest blog posts on PAK1.
Myosin is More than Just a Heavy Lifter
Myosin is a well-known, hexameric molecular motor that is a key cytoskeletal component. It consists of a pair of myosin heavy chain subunits (MHC), a pair of essential myosin light chain subunits (MLC), and a pair of regulatory light chain subunits (R...    Read more.
Read more PAK1 related blogs.