Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Bv, Ca
Applications: ELISA, ICC/IF, IHC
Host: Goat Polyclonal
Species: Hu, Av-Bi
Applications: WB
Host: Mouse Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
P4HA1 encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.
Bioinformatics
| Uniprot |
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
5033 |
| Alternate Names |
- 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase)
- 2-oxoglutarate-4-dioxygenase subunit alpha-1
- 4-PH alpha-1
- alpha polypeptide I
- EC 1.14.11.2
- Procollagen-proline
- prolyl 4-hydroxylase, alpha polypeptide I
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