p23/PTGES3 Products

Antibodies
p23/PTGES3 Antibody (JJ3)
p23/PTGES3 Antibody (JJ3)
Species: Hu, Mu, Rt, Ch, GP, Pm, Rb, Xp
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
Host: Mouse Monoclonal
p23/PTGES3 Antibody (JJ6)
p23/PTGES3 Antibody (JJ6)
NB110-96879
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IP
Host: Mouse Monoclonal
p23/PTGES3 Antibody
p23/PTGES3 Antibody
NBP1-85485
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
p23/PTGES3 Overexpression Lys ...
p23/PTGES3 Overexpression Lysate (...
NBL1-14937
Applications: WB
Proteins
p23/PTGES3 Recombinant Protei ...
p23/PTGES3 Recombinant Protein Ant...
NBP1-85485PEP
Species: Hu
Applications: AC
p23/PTGES3 Recombinant Protei ...
p23/PTGES3 Recombinant Protein Ant...
NBP1-85486PEP
Species: Hu
Applications: AC
Recombinant Human p23/PTGES3 ...
Recombinant Human p23/PTGES3 Protein
NBP1-30281
Species: Hu
Applications: PAGE
RNAi
p23/PTGES3 RNAi
p23/PTGES3 RNAi
H00010728-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Steroid receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Prior to activation, steroid receptors associate with a number of different proteins in both a stable and transient fashion. Steroid receptor complex proteins include heat shock proteins (HSP 70 and HSP 90), immunosuppressant binding proteins called immunophilins (the FK 506 binding proteins, FKBP 52 & FKBP 54 and the cyclosporin binding protein, CyP-40) and at least three other proteins termed p23, p60 and p48. p23 along with HSP 70, HSP 90 and p60, combine with progesterone receptor (PR) as members of a transient intermediate complex. Cloned human p23 encodes a protein of 160 amino acids that is highly conserved between species and shows no homology to previously identified proteins. p23 is a highly acidic phosphoprotein with an aspartic acid-rich C-terminal domain and multiple potential phosphorylation sites. In vitro studies have suggested that p23 binds to HSP90 and is necessary for the binding of HSP 90 and CyP-40 to PR. While neither its exact function nor mechanism of action have been identified, p23 appears to be an important factor in PR function.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Product By Gene ID 10728
Alternate Names
  • Telomerase-binding protein p23
  • unactive progesterone receptor, 23 kD
  • Progesterone receptor complex p23
  • prostaglandin E synthase 3
  • Cytosolic prostaglandin E2 synthase
  • P23cytosolic prostaglandin E synthase
  • cPGESp23
  • TEBPEC 5.3.99.3
  • Hsp90 co-chaperone
  • prostaglandin E synthase 3 (cytosolic)

Diseases related to p23/PTGES3

Discover more about diseases related to p23/PTGES3.

Pseudopregnancy
Hypertrophy
Asthma
Endometrial Polyp
Dysequilibrium Syndrome
Left Ventricular Hypertrophy

Pathways for p23/PTGES3

View related products by pathway and learn more about each of the pathways below.

Decidualization
Parturition
Fertilization
Pathogenesis
Meiosis

Research Areas for p23/PTGES3

Find related products by research area and learn more about each of the different research areas below.

Membrane Trafficking and Chaperones

PTMs for p23/PTGES3

Learn more about PTMs related to p23/PTGES3.

Cleavage

Bioinformatics Tool for p23/PTGES3

Discover related pathways, diseases and genes to p23/PTGES3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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