P-Cadherin Products

Description

The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. R-cadherin (for retinal-cadherin, also designated cadherin-4), which was first identified in the retina of chicken, has been shown to be involved in the development of striated muscle and potentially epithelia in addition to its involvement in retinal development.

Bioinformatics

Uniprot	AAH41846.1 Human CAA45177 Human NM_001793 Human NP_001784 Human P22223 Human Q8BSL6 Mouse
Product By Gene ID	1001
Alternate Names	cadherin 3, P-cadherin (placental) cadherin 3, type 1, P-cadherin (placental) cadherin-3 CDHPcalcium-dependent adhesion protein, placental HJMD PCADP-cadherin Placental cadherin

Research Areas for P-Cadherin

Find related products by research area and learn more about each of the different research areas below.

Cancer