Nup153 Products

Description

Nuclear pore complexes are extremely elaborate structures that mediate the regulated movement of macromolecules between the nucleus and cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are pore complex specific glycoproteins characterized by cytoplasmically oriented O linked N acetylglucosamine residues and numerous repeats of the pentapeptide sequence XFXFG. Nup153 has three distinct domains: a N terminal region within which a pore targeting domain has been identified, a central region containing multiple zinc finger motifs, and a C terminal region containing multiple XFXFG repeats. Nup153 is a possible DNA binding subunit of the nuclear pore complex (NPC). The repeat containing domain may be involved in anchoring components of the pore complex to the pore membrane.

Bioinformatics

Product By Gene ID	9972
Alternate Names	CG4453 dmNup153 dNup153 HNUP153 N153 nuclear pore complex protein hnup153,153 kDa nucleoporin nuclear pore complex protein Nup153 nucleoporin 153kD nucleoporin 153kDa Nucleoporin Nup153 Nup 153 Nup153 Nucleoporin 153 nup153

Research Areas for Nup153

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Signal Transduction

Related Nup153 Blog Posts

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NUP153 & 53BP1: A Novel DNA Repair Pathway Mediating DNA damage is a crucial process, and one of the most important cellular guards against cancer. In response to DNA damage, sophisticated cellular machinery is recruited to repair the breaks, and if it fails, the cell is committed to death. De...    Read more.

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