NTH1 Products

NTH1 Antibody (208521)
NTH1 Antibody (208521)
Species: Hu
Applications: WB
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
NTH1 Antibody
NTH1 Antibody
Species: Hu
Applications: WB
Host: Goat Polyclonal
Formulation Catalog # Availability Price  
Recombinant Human NTH1 His Pr ...
Recombinant Human NTH1 His Protein
Species: Hu
Applications: PAGE


Oxygen radicals damage chromosonal DNA causing cell death and inducing mutations. Although a major focus of oxidatively damaged DNA has centered on the repair of 8-oxo-G, a number of other damaged DNA sites are created by free-radical attack on DNA. The human NTH1 repair protein is one enzyme that has been shown to act on a large number of these other oxidatively damaged DNA sites. A homologue of E. coli Endonuclease III, NTH is a DNA glycosylase with apurinic/apyrimidinic lyase activity. The NTH protein has broad substrate specificity, including numerous ring saturation and fragmentation products of pyrimidines. Research indicates NTH plays a crucial role in removal of oxidative base lesions in mitochondrial DNA.


Uniprot Human
Product By Gene ID 4913
Alternate Names
  • EC
  • endonuclease III-like protein 1
  • OCTS3NTH1nth (E.coli endonuclease III)-like 1
  • nth endonuclease III-like 1 (E. coli)

Research Areas for NTH1

Find related products by research area and learn more about each of the different research areas below.

Base Excision Repair
Chromatin Research
Core ESC-Like Genes
DNA Repair
Stem Cell Markers

PTMs for NTH1

Learn more about PTMs related to NTH1.


Bioinformatics Tool for NTH1

Discover related pathways, diseases and genes to NTH1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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