Applications: IHC, ICC/IF
Host: Mouse Monoclonal
REST, which is short for RE1-silencing transcription factor, locks down neuronal genes in other cells by grabbing onto the DNA and cementing in other molecules, an arrangement that stays intact as non-neuronal cells differentiate into liver, muscle, and other tissues. REST uses a different temporary off mechanism to direct neuronal development. REST is a tumor suppressor gene in epithelial cells and has been found to be mutated in 33 percent of colorectal tumors and cell lines studied. Rest could eventually serve as a marker for diagnosing colorectal and other types of cancer.
|Product By Gene ID
- Neural-restrictive silencer factor
- XBRrepressor binding to the X2 box
- NRSFneuron restrictive silencer factor
- X2 box repressor
- RE1-silencing transcription factor
Bioinformatics Tool for NRSF
Discover related pathways, diseases and genes to NRSF. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.