Hu, Mu, Rt, CaApplications:
WB, Flow, IHC, IHC-P, PEP-ELISAHost:
Species: Hu, Mu, Rt, Po, Bv, Ca, Ch, Gp, Xp, Ze
Host: Rabbit Polyclonal
Applications: WB, ELISA, Flow, ICC/IF
Host: Mouse Monoclonal
Ras (p21), a signal transducer, was first characterized as the transforming genes of Harvey & Kristen sarcoma virus (1). The Ras family (H-Ras, N-Ras, and K-Ras) regulates cell growth, differentiation and apoptosis (2). Switching from an active or resting state, Ras can either bind GTP or GDP respectively. In the triphosphate conformation, Ras will interact with GTPase activating protein (GAP) to increase its activity (3). Mutations in any of the three isoforms can convert these proteins into active oncogenes. Additionally, Ras mutations are found in 30% of all human cancer (4).
|Product By Gene ID
- v-ras neuroblastoma RAS viral oncogene homolog
- N-ras protein part 4
- Transforming protein N-Ras
- GTPase NRas
- neuroblastoma RAS viral (v-ras) oncogene homolog
Bioinformatics Tool for NRAS
Discover related pathways, diseases and genes to NRAS. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.