NRAS Products

Antibodies
NRAS Antibody
NRAS Antibody
NB100-94887
Species: Hu, Rt
Applications: WB, IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
NRAS Antibody (5G7)
NRAS Antibody (5G7)
NBP2-45860
Species: Hu
Applications: WB, IHC
Host: Mouse monoclonal
Lysates
NRAS Overexpression Lysate (N ...
NRAS Overexpression Lysate (Native)
NBL1-13785
Applications: WB
Proteins
NRAS Recombinant Protein
NRAS Recombinant Protein
NBP1-41158
Species: Hu
Applications: PAGE
RNAi
NRAS RNAi
NRAS RNAi
H00004893-R01
Species: Hu

Description

Ras (p21), a signal transducer, was first characterized as the transforming genes of Harvey & Kristen sarcoma virus (1). The Ras family (H-Ras, N-Ras, and K-Ras) regulates cell growth, differentiation and apoptosis (2). Switching from an active or resting state, Ras can either bind GTP or GDP respectively. In the triphosphate conformation, Ras will interact with GTPase activating protein (GAP) to increase its activity (3). Mutations in any of the three isoforms can convert these proteins into active oncogenes. Additionally, Ras mutations are found in 30% of all human cancer (4).

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Product By Gene ID 4893
Alternate Names
  • HRAS1
  • NS6
  • v-ras neuroblastoma RAS viral oncogene homolog
  • ALPS4
  • N-ras protein part 4
  • Transforming protein N-Ras
  • GTPase NRas
  • N-ras
  • NRAS1
  • neuroblastoma RAS viral (v-ras) oncogene homolog

Research Areas for NRAS

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
Cell Cycle and Replication
mTOR Pathway

Bioinformatics Tool for NRAS

Discover related pathways, diseases and genes to NRAS. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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