NRAS Products

Antibodies
NRAS Antibody
NRAS Antibody
NBP2-19581
Species: Hu, Mu, Rt, Po, Bv, Ca, Ch, Gp, Xp, Ze
Applications: WB
Host: Rabbit Polyclonal
Lysates
NRAS Overexpression Lysate
NRAS Overexpression Lysate
NBL1-13785
Species: Hu
Applications: WB
Proteins
Recombinant Human NRAS Protei ...
Recombinant Human NRAS Protein
NBP1-41158
Species: Hu
Applications: PAGE

Description

Ras (p21), a signal transducer, was first characterized as the transforming genes of Harvey & Kristen sarcoma virus (1). The Ras family (H-Ras, N-Ras, and K-Ras) regulates cell growth, differentiation and apoptosis (2). Switching from an active or resting state, Ras can either bind GTP or GDP respectively. In the triphosphate conformation, Ras will interact with GTPase activating protein (GAP) to increase its activity (3). Mutations in any of the three isoforms can convert these proteins into active oncogenes. Additionally, Ras mutations are found in 30% of all human cancer (4).

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Product By Gene ID 4893
Alternate Names
  • ALPS4
  • GTPase NRas
  • HRAS1
  • neuroblastoma RAS viral (v-ras) oncogene homolog
  • N-ras protein part 4
  • N-ras
  • NRAS1
  • NS6
  • Transforming protein N-Ras
  • v-ras neuroblastoma RAS viral oncogene homolog

Research Areas for NRAS

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
Cell Cycle and Replication
mTOR Pathway

Bioinformatics Tool for NRAS

Discover related pathways, diseases and genes to NRAS. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related NRAS Blog Posts

Check out the latest blog posts on NRAS.
Autophagy and RAS signaling: Clinical implications
By Christina Towers, PhD The cellular recycling process known as autophagy is currently being targeted in over 60 clinical trials focused on treating different types of cancer1. To date, the only autophagy-targeted ...    Read more.
Read more NRAS related blogs.