NPRA/NPR1 Products

Antibodies
NPRA/NPR1 Antibody
NPRA/NPR1 Antibody
NBP1-31333
Species: Hu, Mu, Rt, Bv
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
NPRA/NPR1 Antibody (488620) [ ...
NPRA/NPR1 Antibody (488620) [Uncon...
MAB3974
Species: Mu
Applications: IHC
Host: Rat Monoclonal
NPRA/NPR1 Antibody (377018) [ ...
NPRA/NPR1 Antibody (377018) [Uncon...
MAB48601
Species: Hu
Applications: IHC
Host: Mouse Monoclonal
Lysates
NPRA/NPR1 Overexpression Lysa ...
NPRA/NPR1 Overexpression Lysate (N...
NBL1-13754
Applications: WB
Proteins
Recombinant Human NPRA/NPR1 P ...
Recombinant Human NPRA/NPR1 Protein
H00004881-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
NPRA/NPR1 RNAi
NPRA/NPR1 RNAi
H00004881-R04
Species: Hu
Applications: RNAi, RNAi SP

Description

Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 (PubMed 7982997)). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).(supplied by OMIM)

Bioinformatics

Uniprot Human
Human
Human
Product By Gene ID 4881
Alternate Names
  • GC-A
  • natriuretic peptide receptor A
  • ANPR-A
  • natriuretic peptide A type receptor
  • ANP-A
  • atrionatriuretic peptide receptor A
  • Guanylate cyclase A
  • atrial natriuretic peptide receptor 1
  • Atrial natriuretic peptide receptor type A
  • NPRA
  • GUCY2A
  • GUC2A
  • ANPa
  • ANPRAEC 4.6.1.2
  • NPR-A
  • natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptidereceptor A)

Research Areas for NPRA/NPR1

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase

Bioinformatics Tool for NPRA/NPR1

Discover related pathways, diseases and genes to NPRA/NPR1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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