NPRA/NPR1 Products

NPRA/NPR1 Antibody
NPRA/NPR1 Antibody
Species: Hu, Mu, Rt, Rb, Bv
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
NPRA/NPR1 Antibody (377018) [ ...
NPRA/NPR1 Antibody (377018) [Uncon...
Species: Hu
Applications: IHC
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
NPRA/NPR1 Antibody (488620) [ ...
NPRA/NPR1 Antibody (488620) [Uncon...
Species: Mu
Applications: IHC
Host: Rat Monoclonal
Formulation Catalog # Availability Price  
NPRA/NPR1 Overexpression Lysa ...
NPRA/NPR1 Overexpression Lysate
Species: Hu
Applications: WB
Recombinant Mouse NPRA/NPR1 P ...
Recombinant Mouse NPRA/NPR1 Protei...
Species: Mu
Formulation Catalog # Availability Price  
Recombinant Human NPRA/NPR1 G ...
Recombinant Human NPRA/NPR1 GST (N...
Species: Hu
Applications: WB, ELISA, PA, AP
NPRA/NPR1 Recombinant Protein ...
NPRA/NPR1 Recombinant Protein Antigen
Species: Hu
Applications: AC


Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 (PubMed 7982997)). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).(supplied by OMIM)


Uniprot Human
Product By Gene ID 4881
Alternate Names
  • ANPa
  • ANP-A
  • ANPR-A
  • atrial natriuretic peptide receptor 1
  • Atrial natriuretic peptide receptor type A
  • atrionatriuretic peptide receptor A
  • GC-A
  • Guanylate cyclase A
  • GUC2A
  • GUCY2A
  • natriuretic peptide A type receptor
  • natriuretic peptide receptor A
  • natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptidereceptor A)
  • NPRA
  • NPR-A

Research Areas for NPRA/NPR1

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Protein Kinase

Bioinformatics Tool for NPRA/NPR1

Discover related pathways, diseases and genes to NPRA/NPR1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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