NOX1 Products

Description

Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Bioinformatics

Product By Gene ID	27035
Alternate Names	EC 1.6.3 GP91-2 Mitogenic oxidase 1 MOX-1 MOX1NADH/NADPH mitogenic oxidase subunit P65-MOX NADPH oxidase 1 NADPH oxidase homolog-1 NOH1 NOH1mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating) NOH-1NADPH oxidase 1 variant NOH-1L NOX1 NOX-1

Research Areas for NOX1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Biology
Direct Reversal of DNA Damage
Immunology
Signal Transduction

Related NOX1 Blog Posts

Check out the latest blog posts on NOX1.

Toll-like receptors in the intestinal epithelial cells By Jamshed Arslan, Pharm. D., PhD. Toll-like receptors (TLRs) are microbe-sensing proteins that act as first responders to danger signals. TLRs help the intestinal epithelial cells (IECs) recognize commensal bacteria ...    Read more.

Read more NOX1 related blogs.