Nociceptin Products

Antibodies
Nociceptin Antibody
Nociceptin Antibody
NB100-1619
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
Nociceptin Antibody
Nociceptin Antibody
NB100-1659
Species: Hu, Mu, Rt
Applications: IHC, IHC-P
Host: Guinea Pig Polyclonal
Nociceptin Antibody
Nociceptin Antibody
NBP1-59307
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
Nociceptin Overexpression Lys ...
Nociceptin Overexpression Lysate (...
NBL1-14553
Applications: WB
Proteins
Nociceptin Recombinant Protei ...
Nociceptin Recombinant Protein Ant...
NBP2-58314PEP
Species: Hu
Applications: B/N, Ctrl
Recombinant Human Nociceptin ...
Recombinant Human Nociceptin Protein
NBP2-23359
Species: Hu
Applications: PAGE

Description

Nociceptin (Orphanin FQ, OFQ), a heptadecapeptide peptide, has been designated as an endogenous ligand for the ORL1 receptor. The amino acid sequence of nociceptin hashomology with other opioid peptides, especially the prodynorphin fragment dynorphin A, suggesting a close evolutionary relationship between the precursors. A diffuse distribution throughout the brain is seen with binding studies and in situ hybridization suggesting an extensive role for nociceptin in a multitude of CNS functions. Immunocytochemical localizations in rat spinal cord have demonstrated nociceptin abundance in superficial dorsal horn, lateral spinal nucleus and the region dorsal to the central canal. Nociceptin immunoreactivity was not affected by dorsal rhizotomy, indicating that in spinal cord the peptide is produced by central rather than primary afferent neurons. The localization is supported by its function in processing of nociceptive signals.

Bioinformatics

Uniprot Human
Human
Human
Product By Gene ID 5368
Alternate Names
  • nocistatin
  • P
  • nociceptin
  • OFQ
  • PPNOC
  • propronociceptin
  • prepronociceptin

Pathways for Nociceptin

View related products by pathway and learn more about each of the pathways below.

Neurogenesis
Autolysis
Pathogenesis
Inflammatory Response

Research Areas for Nociceptin

Find related products by research area and learn more about each of the different research areas below.

Neuroscience
Signal Transduction

Bioinformatics Tool for Nociceptin

Discover related pathways, diseases and genes to Nociceptin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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