NK1R Products

Antibodies
Antibody Packs
NK1R Antibody Pack
NK1R Antibody Pack
NB100-912
Species: Hu, Mu, Rt, Gp
Applications: WB, IHC, IHC-P
Host: Rabbit
ELISA Kits
Rat NK1R ELISA Kit (Colorimet ...
Rat NK1R ELISA Kit (Colorimetric)
NBP2-80293
Species: Rt
Applications: ELISA
Human NK1R ELISA Kit (Colorim ...
Human NK1R ELISA Kit (Colorimetric)
NBP2-80291
Species: Hu
Applications: ELISA
Mouse NK1R ELISA Kit (Colorim ...
Mouse NK1R ELISA Kit (Colorimetric)
NBP2-80292
Species: Mu
Applications: ELISA
Lysates
NK1R Overexpression Lysate
NK1R Overexpression Lysate
NBL1-16672
Species: Hu
Applications: WB
Proteins
NK1R Antibody Blocking Peptid ...
NK1R Antibody Blocking Peptide
NB300-101PEP
Species: Rt
Applications: AC
NK1R Antibody Blocking Peptid ...
NK1R Antibody Blocking Peptide
NB300-119PEP
Species: Hu
Applications: AC
Recombinant Human NK1R GST (N ...
Recombinant Human NK1R GST (N-Term...
H00006869-Q02
Species: Hu
Applications: WB, ELISA, PA, AP

Description

The Neurokinins, also known as Tachykinins, belong to an evolutionary conserved family of peptide neurotransmitters that share a c-terminal sequence and have an established role in neurotransmission. The mammalian tachykinins include substance P (NK1), neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.

Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C).

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Human
Human
Rat
Product By Gene ID 6869
Alternate Names
  • NK-1R
  • tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor)
  • NKIR
  • TAC1Rtachykinin 1 receptor (substance P receptor, neurokinin 1 receptor)
  • SPRsubstance-P receptor
  • NK1Rneurokinin 1 receptor
  • tachykinin receptor 1NK-1 receptor

Research Areas for NK1R

Find related products by research area and learn more about each of the different research areas below.

GPCR
Neuronal Cell Markers
Neuroscience
Neurotransmission

PTMs for NK1R

Learn more about PTMs related to NK1R.

Cleavage

Bioinformatics Tool for NK1R

Discover related pathways, diseases and genes to NK1R. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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