NFYB Products

Description

The protein encoded by the NFYB gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. (provided by RefSeq)

Bioinformatics

Uniprot	AAH05317 Human NM_006166 Human P25208 Human
Product By Gene ID	4801
Alternate Names	Transcription factor NF-Y, B subunit Nuclear transcription factor Y subunit B nuclear transcription factor Y subunit beta CBF-A NF-YBCCAAT-binding transcription factor subunit A HAP3CBF-B CAAT box DNA-binding protein subunit B nuclear transcription factor Y, beta

Diseases related to NFYB

Discover more about diseases related to NFYB.

Malignant Neoplasms
Neoplasms
Leukemia
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Ataxia
Swine Diseases
Gait, Drop Foot
Leukemia, Myelocytic, Acute
Fibrosis
Cardiovascular Diseases
Myeloid Leukemia
L1 Acute Lymphoblastic Leukemia
Myoclonus
Neuroblastoma
Gait Ataxia
Schizophrenia
Myoclonic Epilepsies, Progressive

Pathways for NFYB

View related products by pathway and learn more about each of the pathways below.

Cell Cycle
Cell Proliferation
Localization
Transport
Regulation Of Cell Cycle
Aging
Immune Response
Cell Cycle Arrest
Transcriptional Attenuation
Senescence
Methylation
Replicative Senescence
Cell Death
Chromatin Modification
Pathogenesis
Meiosis
Chromatin Remodeling

Research Areas for NFYB

Find related products by research area and learn more about each of the different research areas below.

Stem Cell Markers

PTMs for NFYB

Learn more about PTMs related to NFYB.

Acetylation
Phosphorylation
Cleavage
Oxidation
Methylation
Myristoylation

Bioinformatics Tool for NFYB

Discover related pathways, diseases and genes to NFYB. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.