NFYA Products

Description

The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq]

Bioinformatics

Product By Gene ID	4800
Alternate Names	CAAT box DNA-binding protein subunit A CBF-A CBF-B CCAAT-binding transcription factor subunit B FLJ11236 HAP2 CCAAT-binding protein HAP2 NF-YACAAT-box DNA binding protein subunit A Nuclear transcription factor Y subunit A nuclear transcription factor Y subunit alpha nuclear transcription factor Y, alpha Transcription factor NF-Y, A subunit

Research Areas for NFYA

Find related products by research area and learn more about each of the different research areas below.

Cancer
Signal Transduction
Transcription Factors and Regulators