NFYA Products

Antibodies
NFYA Antibody
NFYA Antibody
NBP2-19533
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
NFYA Antibody
NFYA Antibody
NB600-481
Species: Hu, Mu
Applications: WB, ELISA, GS, IHC, IHC-P
Host: Rabbit Polyclonal
NFYA Antibody
NFYA Antibody
NBP2-48977
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Lysates
NFYA Overexpression Lysate (N ...
NFYA Overexpression Lysate (Native)
NBL1-13627
Applications: WB
NFYA Overexpression Lysate (N ...
NFYA Overexpression Lysate (Native)
NBL1-13628
Applications: WB
Proteins
NFYA Partial Recombinant Prot ...
NFYA Partial Recombinant Protein
H00004800-Q01
Species: Hu
Applications: WB, ELISA, PA
NFYA Recombinant Protein
NFYA Recombinant Protein
H00004800-P01
Species: Hu
Applications: WB, ELISA, PA
NFYA Recombinant Protein Anti ...
NFYA Recombinant Protein Antigen
NBP2-48977PEP
Species: Hu
Applications: AC
RNAi
NFYA RNAi
NFYA RNAi
H00004800-R02
Species: Hu
Applications: RNAi, RNAi SP
NFYA RNAi
NFYA RNAi
H00004800-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The Y box is a CCAAT box which is bound by the heteromeric DNA binding protein, NFY (also known as CBF and CP1). Unlike the transcription factors C/EBP and CTF/NF1 which also bind CCAAT like sequences, NFY exhibits a strict binding requirement for this pentanucleotide sequence. Binding sites for this factor have been described for nearly 30% of all eukaryotic genes. Y/CCAAT sequences were frequently observed in the promoter proximal sequences. NF-Y is composed of 3 separate subunits (A,B and C) each of which is required for DNA binding. Each subunit has remained highly conserved throughout evolution. In fact, homologous yeast subunits can substitute for mammalian NF-Y in DNA-binding assays. The conserved core sequences of NF-YB and NF-YC contain a 70 aa region similar to the histone fold motif of nucleosomes H2A and H2B. The unique structure and evolutionary conservation of this transcription factor suggests that it plays a fundamental role in the readout of eukaryotic genetic information.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Product By Gene ID 4800
Alternate Names
  • CBF-A
  • Transcription factor NF-Y, A subunit
  • CAAT box DNA-binding protein subunit A
  • nuclear transcription factor Y subunit alpha
  • Nuclear transcription factor Y subunit A
  • HAP2 CCAAT-binding protein
  • HAP2
  • CCAAT-binding transcription factor subunit B
  • CBF-B
  • NF-YACAAT-box DNA binding protein subunit A
  • FLJ11236
  • nuclear transcription factor Y, alpha

Research Areas for NFYA

Find related products by research area and learn more about each of the different research areas below.

Cancer
Signal Transduction
Transcription Factors and Regulators

Bioinformatics Tool for NFYA

Discover related pathways, diseases and genes to NFYA. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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