NFKBIL2 Products

Antibodies
NFKBIL2 Antibody - BSA Free
NFKBIL2 Antibody - BSA Free
NBP1-87764
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
NFKBIL2 Antibody - BSA Free
NFKBIL2 Antibody - BSA Free
NBP2-48847
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
NFKBIL2 Antibody - BSA Free
NFKBIL2 Antibody - BSA Free
NBP3-29555
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Proteins
NFKBIL2 Recombinant Protein A ...
NFKBIL2 Recombinant Protein Antigen
NBP2-48847PEP
Species: Hu
Applications: AC
NFKBIL2 Recombinant Protein A ...
NFKBIL2 Recombinant Protein Antigen
NBP1-87764PEP
Species: Hu
Applications: AC

Description

Sharing some sequence similarities with IKBKB, NF-kappa-B inhibitor-like protein 2 (NFKBIL2) belongs to the Tonsoku family. Also known as TONSL, the protein encoded by this gene may bind NF-kappa-B complex and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Additionally, NFKBIL2 is a component of the MMS22L-TONSL complex. Used during DNA replication, this complex is essential for promoting homologous recombination repair of replication fork double strand breaks. NFKBIL2 is known to interact with MMS22L, MCM4, SSRP1, GSK3B and MCM2. Diseases associated with this gene include t-cell leukemia, psoriasis, breast cancer, atherosclerosis, leukemia and immunodeficiency.

Bioinformatics

Uniprot Human
Human
Human
Product By Gene ID 4796
Alternate Names
  • IkappaBR
  • I-kappa-B-related protein
  • IKBRFLJ40087
  • Inhibitor of kappa B-related protein
  • NF-kappa-B inhibitor-like protein 2
  • NFKBIL2tonsoku-like protein
  • Nuclear factor of kappa light polypeptide gene enhancer in B-cellsinhibitor-like 2ikappaBR
  • tonsoku-like, DNA repair protein