NALP12 Products

Antibodies
NALP12 Antibody
NALP12 Antibody
NB100-56157
Species: Hu
Applications: WB, IHC, IHC-Fr, IHC-P, IP
Host: Rabbit Polyclonal
NALP12 Antibody
NALP12 Antibody
NBP1-76293
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, ICC
Host: Rabbit Polyclonal
NALP12 Antibody
NALP12 Antibody
NBP1-85555
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
NALP12 Overexpression Lysate ...
NALP12 Overexpression Lysate (Native)
NBL1-13673
Applications: WB
Proteins
NALP12 Partial Recombinant Pr ...
NALP12 Partial Recombinant Protein
H00091662-Q01
Species: Hu
Applications: WB, ELISA, PA
NALP12 Recombinant Protein An ...
NALP12 Recombinant Protein Antigen
NBP1-85555PEP
Species: Hu
Applications: AC
NALP12 Peptide
NALP12 Peptide
NBP1-76293PEP
Species: Hu
Applications: AC
RNAi
NALP12 RNAi
NALP12 RNAi
H00091662-R01
Species: Hu
Applications: RNAi, RNAi SP
NALP12 RNAi
NALP12 RNAi
H00091662-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP12, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes. NALP12 may mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK.

Bioinformatics

Uniprot Human
Human
Human
Product By Gene ID 91662
Alternate Names
  • PYRIN-containing APAF1-like protein 7
  • Monarch-1
  • Regulated by nitric oxide
  • nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domaincontaining 12
  • NACHT, leucine rich repeat and PYD containing 12
  • NACHT, LRR and PYD domains-containing protein 12
  • RNO2
  • NALP12LRR and PYD containing protein 12
  • PYPAF7Monarch1
  • FCAS2
  • NLR family, pyrin domain containing 12

Research Areas for NALP12

Find related products by research area and learn more about each of the different research areas below.

Apoptosis

PTMs for NALP12

Learn more about PTMs related to NALP12.

Phosphorylation
Acetylation

Bioinformatics Tool for NALP12

Discover related pathways, diseases and genes to NALP12. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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