Species: Rt
Applications: WB, B/N
Host: Goat Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
Species: Hu
Applications: Bioactivity
Species: Pm-Cm
Applications: Bioactivity
Species: Pm-Cm
Applications: Bioactivity
Description
Intercellular communication is often mediated by receptors on the surface of one cell that recognize and are activated by specific protein ligands released by other cells. Members of one class of cell surface receptors, receptor tyrosine kinases (RTKs), are characterized by having a cytoplasmic domain containing intrinsic tyrosine kinase activity. This kinase activity is regulated by the binding of a cognate ligand to the extracellular portion of the receptor. DeChiara et al. (1996) [PubMed 8653786] noted that the RTKs, known to be expressed in cell type-specific fashions, play a role critical for the growth and differentiation of those cell types. For example, members of the neural-specific TRK family that recognize nerve growth factor are absolutely required for the survival and development of discrete neuronal subpopulations, and the receptor tyrosine kinases TIE1 (MIM 600222) and TIE2 (MIM 600221) play a critical role in the development of normal blood vessels.[supplied by OMIM]
Bioinformatics
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
4593 |
| Alternate Names |
- EC 2.7.10
- EC 2.7.10.1
- MGC126323
- MGC126324
- muscle, skeletal, receptor tyrosine kinase
- MuSK
- skeletal receptor tyrosine-protein kinase
|
Bioinformatics Tool for MuSK
Discover related pathways, diseases and genes to MuSK. Need help? Read the
Bioinformatics Tool Guide for instructions on using this tool.
-Immunocytochemistry-Immunofluorescence-NBP1-47441-img0006.jpg)
-Immunohistochemistry-Paraffin-NBP1-47441-img0004.jpg)
-Immunocytochemistry-Immunofluorescence-NBP1-47441-img0005.jpg)
![Binding Activity MuSK [Unconjugated]](http://images.novusbio.com/fullsize2/10189-mk_recombinant-human-musk-his-tag-protein-cf-binding-activity-1522021105911.jpg)
![SDS-PAGE MuSK [Unconjugated]](http://images.novusbio.com/fullsize2/10189-mk_recombinant-human-musk-his-tag-protein-cf-sds-page-322021132027.jpg)
![Binding Activity MuSK [Unconjugated]](http://images.novusbio.com/fullsize2/11153-mk_recombinant-cynomolgus-monkey-musk-his-tag-protein-cf-binding-activity-115202284155.jpg)
![SDS-PAGE MuSK [Unconjugated]](http://images.novusbio.com/fullsize2/11153-mk_recombinant-cynomolgus-monkey-musk-his-tag-protein-cf-sds-page-115202284618.jpg)
![Binding Activity MuSK [Unconjugated]](http://images.novusbio.com/fullsize2/11122-mk_recombinant-cynomolgus-monkey-musk-fc-chimera-protein-cf-binding-activity-264202211540.jpg)
![SDS-PAGE MuSK [Unconjugated]](http://images.novusbio.com/fullsize2/11122-mk_recombinant-cynomolgus-monkey-musk-fc-chimera-protein-cf-sds-page-2642022111018.jpg)