MMP-11 Products

Antibodies
MMP-11 Antibody
MMP-11 Antibody
NB100-91870
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
MMP-11 Antibody (135421)
MMP-11 Antibody (135421)
MAB3657
Species: Hu
Applications: ICFlow
Host: Mouse Monoclonal
MMP-11 Antibody
MMP-11 Antibody
NBP2-49575
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Proteins
MMP-11 Recombinant Protein An ...
MMP-11 Recombinant Protein Antigen
NBP2-49575PEP
Species: Hu
Applications: AC
MMP-11 Recombinant Protein
MMP-11 Recombinant Protein
P4554
Species: Hu
Applications: Func, PAGE
RNAi
MMP-11 RNAi
MMP-11 RNAi
H00004320-R01
Species: Hu

Description

The matrix metalloproteinases are a tightly regulated family of enzymes that degrade extracellular matrix and basement membrane components. Recent evidence suggests that these proteases and their specific inhibitors play important roles in normal developmental processes and in pathological conditions (1). MMP-11 (stromelysin-3), a new member of the matrix metalloproteinase family, is expressed in tissues undergoing the active remodeling associated with embryonic development, wound healing and tumor invasion. But like all other members of the matrix metalloproteinase gene family, stromelysin-3 is synthesized as an inactive precursor that must be processed to its mature form in order to express enzymic activity (2). MMP-11, like an inflammatory mediator, may exert a chemotactic influence on macrophages which aggregate in the mesangium; MMP-11 is not likely to have a parallel mitogenic or antifibrotic effect in diseased glomeruli (3).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 4320
Alternate Names
  • EC 3.4.24.24
  • ST3
  • EC 3.4.24
  • SL-3
  • EC 3.4.24.-
  • MMP-11
  • stromelysin-3
  • Matrix metalloproteinase-11
  • stromelysin III
  • matrix metalloproteinase 11 (stromelysin 3)
  • STMY3stromelysin 3
  • matrix metallopeptidase 11 (stromelysin 3)

Research Areas for MMP-11

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Extracellular Matrix

PTMs for MMP-11

Learn more about PTMs related to MMP-11.

Cleavage
Phosphorylation
Acetylation
Methylation

Bioinformatics Tool for MMP-11

Discover related pathways, diseases and genes to MMP-11. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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