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MKK4/MEK4 Products

Antibodies
MKK4/MEK4 Antibody - BSA Free ...
MKK4/MEK4 Antibody - BSA Free
Species: Hu, Mu, Rt
Applications: WB, IHC, KO
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
MKK4/MEK4 Antibody (HL1888) - ...
MKK4/MEK4 Antibody (HL1888) - Azid...
NBP3-25675
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Monoclonal
Lysates
MKK4/MEK4 Overexpression Lysa ...
MKK4/MEK4 Overexpression Lysate
NBL1-12850
Species: Hu
Applications: WB
Proteins
MKK4/MEK4 Recombinant Protein ...
MKK4/MEK4 Recombinant Protein Antigen
NBP2-57194PEP
Species: Hu
Applications: AC

Description

MKK4, a MAP2K type protein kinase, is a member of the stress-activated protein kinase (SAPK) pathways which convey pro-apoptotic signals. MKK4 is activated by MEKK1 or MEKK2, and to a lesser extent by GCK or ASK1. MKK4 phosphorylates and activates JNK1, JNK2 and p38. MKK4 deficiency in mouse embryos led to lethality after embryonic day 12.5 and was associated with abnormal liver development. Additional studies have linked MKK4 to tumor suppression.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot
Product By Gene ID 6416
Alternate Names
  • c-Jun N-terminal kinase kinase 1
  • dual specificity mitogen-activated protein kinase kinase 4
  • JNK activating kinase 1
  • JNK-activated kinase 1
  • JNK-activating kinase 1
  • JNKK
  • JNKK1
  • JNKK1MAPK/ERK kinase 4
  • MAP kinase kinase 4
  • MAP2K4
  • MAPKK4
  • MEK4
  • MEK4MEK 4
  • mitogen-activated protein kinase kinase 4
  • MKK4
  • MKK4SAPK/ERK kinase 1
  • PRKMK4
  • PRKMK4MAPKK 4
  • SEK1
  • SERK1
  • SERK1EC 2.7.12.2

Research Areas for MKK4/MEK4

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Phospho-Specific
Protein Kinase