MKK3/MEK3 Products

Antibodies
MKK3/MEK3 [p Ser189] Antibody ...
MKK3/MEK3 [p Ser189] Antibody
NB100-82048
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
MKK3/MEK3 Antibody (275909) [ ...
MKK3/MEK3 Antibody (275909) [Uncon...
MAB2515
Species: Hu, Mu, Rt
Applications: WB, ICC
Host: Mouse Monoclonal
MKK3/MEK3 Antibody (1D10)
MKK3/MEK3 Antibody (1D10)
H00005606-M02
Species: Hu
Applications: WB, ELISA, IHC, IHC-P, IP
Host: Mouse Monoclonal
Antibody Pairs
MKK3/MEK3 Antibody Pair
MKK3/MEK3 Antibody Pair
H00005606-PW1
Species: Hu
Applications: WB, IP
Lysates
MKK3/MEK3 Overexpression Lysa ...
MKK3/MEK3 Overexpression Lysate (N...
NBL1-12848
Applications: WB
MKK3/MEK3 Overexpression Lysa ...
MKK3/MEK3 Overexpression Lysate (D...
H00005606-T01
Applications: WB
Proteins
MKK3/MEK3 Recombinant Protein ...
MKK3/MEK3 Recombinant Protein
NBP1-51069
Applications: PAGE
RNAi
MKK3/MEK3 RNAi
MKK3/MEK3 RNAi
H00005606-R05
Species: Hu
MKK3/MEK3 RNAi
MKK3/MEK3 RNAi
H00005606-R06
Species: Hu
MKK3/MEK3 RNAi
MKK3/MEK3 RNAi
H00005606-R04
Species: Hu

Description

Mitogen-acitvated protein kinase kinase 3 (MKK3) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MAPKs require dual phosphorylation on threonine and tyrosine residues, an activation step carried out by MAPK kinase (1-2). MKK3, closely related to MKK6, efficiently phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines and environmental stress but not JNK or ERK (3). MKK3 is activated by mitogenic and environ-mental stress stimulus as well as by insulin. MKK3 is necessary for the expression of glucose transporter and participates in the MAP kinase- mediated signaling cascade (4).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 5606
Alternate Names
  • MAPK/ERK kinase 3
  • mitogen activated protein kinase kinase 3
  • MAP kinase kinase 3
  • MAPKK3PRKMK3dual specificity mitogen-activated protein kinase kinase 3
  • MKK3EC 2.7.12.2
  • MEK3MEK 3
  • MAPKK 3
  • mitogen-activated protein kinase kinase 3

Research Areas for MKK3/MEK3

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Hypoxia
Lipid and Metabolism
Phospho-Specific
Protein Kinase

Bioinformatics Tool for MKK3/MEK3

Discover related pathways, diseases and genes to MKK3/MEK3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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