MITF Products

MITF Antibody
MITF Antibody
Species: Hu
Applications: WB, ChIP, IHC, IHC-P
Host: Rabbit Polyclonal
MITF Antibody
MITF Antibody
Species: Hu
Applications: WB, IHC
Host: Goat Polyclonal
Formulation Catalog # Availability Price  
MITF Overexpression Lysate
MITF Overexpression Lysate
Species: Hu
Applications: WB
Recombinant Human MITF GST (N ...
Recombinant Human MITF GST (N-Term...
Species: Hu
Applications: WB, ELISA, PA, AP
MITF Recombinant Protein Anti ...
MITF Recombinant Protein Antigen
Species: Hu
Applications: AC


MITF (microphthalmia-associated transcription factor) is a melanocytic nuclear protein that contains basic helix-loop-helix (HLH) and leucine zipper (LZ) domains. These protein motifs are frequently observed in other transcription factors and are particularly common to members of the Myc family. MITF can directly associate with DNA as a homodimer. It is required for the development and differentiation of melanocytes. Its expression is upregulated by cAMP and cAMP dependent pathways. MITF activates several different gene promoters by binding to their E-boxes. Tyrosinase, TRP-1 and TRP-2 are pigment synthesis genes activated by MITF. When MITF is phosphorylated on Serine 73 (via the MAPK pathway), it associates with coactivators of the p300/CBP family and enhances transcription. MITF has several isoforms including MITF-M which is specifically expressed in melanocytes. In Mitfdeficient mice there is a complete absence of melanocytes.


Entrez Mouse
Uniprot Human
Product By Gene ID 4286
Alternate Names
  • BHLHE32
  • bHLHe32MI
  • Class E basic helix-loop-helix protein 32
  • microphthalmia-associated transcription factor
  • Waardenburg syndrome, type 2A
  • WS2A

Bioinformatics Tool for MITF

Discover related pathways, diseases and genes to MITF. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

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