mGluR8 Products

Antibodies
mGluR8 Antibody (476410)
mGluR8 Antibody (476410)
MAB5277
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
mGluR8 Antibody
mGluR8 Antibody
NLS925
Species: Hu, Mu, Rt, Bt, Eq, Mk, Pm, Chicken, Opossum
Applications: IHC-P
Host: Rabbit Polyclonal
mGluR8 Antibody
mGluR8 Antibody
NLS922
Species: Hu, Mu, Rt, Bt, Ca, Ch, Eq, Ha, Mk, Pm, Rb, Sh, Opossum
Applications: IHC-P, ICC
Host: Rabbit Polyclonal
Lysates
mGluR8 Overexpression Lysate ...
mGluR8 Overexpression Lysate (Native)
NBL1-11352
Applications: WB
mGluR8 Overexpression Lysate ...
mGluR8 Overexpression Lysate (Native)
NBP2-11380
Applications: WB
Proteins
mGluR8 Partial Recombinant Pr ...
mGluR8 Partial Recombinant Protein
H00002918-Q01
Species: Hu
Applications: WB, ELISA, PA
mGluR8 Recombinant Protein An ...
mGluR8 Recombinant Protein Antigen
NBP2-14073PEP
Species: Hu
Applications: AC
mGluR8 Recombinant Protein
mGluR8 Recombinant Protein
H00002918-G01
Species: Hu
RNAi
mGluR8 RNAi
mGluR8 RNAi
H00002918-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

The mGluR proteins (metabotropic glutamate receptors) are members of the G protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR1 and mGluR5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. GLuR-8 is a group III metabotropic glutamate receptor. In response to glutamate stimulation, GLuR-8 activates GTP-binding proteins that modulate second-messenger cascades. Alternative splicing of this integral membrane protein produces three isoforms: a, b and c. Human GLuR-8 maps to q31.3-q32.1 of chromosome 7.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 2918
Alternate Names
  • mGluR8
  • MGC126724
  • metabotropic glutamate receptor 8
  • FLJ41058
  • glutamate metabotropic receptor 8
  • mGlu8
  • GPRC1HMGLUR8GLUR8
  • glutamate receptor, metabotropic 8

Pathways for mGluR8

View related products by pathway and learn more about each of the pathways below.

Nodulation
Circadian Rhythm
Nitrogen Fixation
Aging
Cognition
Pathogenesis
Localization
Oncogenesis

Research Areas for mGluR8

Find related products by research area and learn more about each of the different research areas below.

GPCR
Metabotropic Glutamate Receptors
Neuronal Cell Markers
Neuroscience
Neurotransmission

PTMs for mGluR8

Learn more about PTMs related to mGluR8.

Phosphorylation

Bioinformatics Tool for mGluR8

Discover related pathways, diseases and genes to mGluR8. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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