MED26 Products

Antibodies
MED26 Antibody (2G10)
MED26 Antibody (2G10)
H00009441-M06
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
MED26 Antibody
MED26 Antibody
H00009441-D01P
Species: Hu
Applications: WB, ELISA
Host: Rabbit Polyclonal
Lysates
MED26 Overexpression Lysate ( ...
MED26 Overexpression Lysate (Denat...
H00009441-T02
Species: Hu
Applications: WB
MED26 Overexpression Lysate ( ...
MED26 Overexpression Lysate (Denat...
H00009441-T01
Species: Hu
Applications: WB
Proteins
MED26 Partial Recombinant Pro ...
MED26 Partial Recombinant Protein
H00009441-Q01
Species: Hu
Applications: WB, ELISA, PA
MED26 Recombinant Protein
MED26 Recombinant Protein
H00009441-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
MED26 RNAi
MED26 RNAi
H00009441-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase. These complexes include CRSP (for cofactor required for Sp1 activation), which is required, in conjunction with TAFIIs, for transcriptional activation by Sp1. CRSP is ubiquitously expressed in various tissues and functions as a multimeric complex that consists of nine distinct subunits. Several members of the CRSP family share sequence similarity with multiple components of the yeast transcriptional mediator proteins, including CRSP150, which is related to yeast Rgr1, and CRSP70, which is similar to the elongation factor TFIIS. CRSP77 and CRSP150 are also related to proteins within the putative murine mediator complex, while CRSP130 and CRSP34 are largely unrelated to either murine or yeast proteins. CRSP subunits also associate with larger multimeric coactivaor complexes, including ARC/DRI, which binds directly to SREBP and nuclear hormone receptors to facilitate transcription, and with NAT, a polymerase II-interacting complex that represses activated transcription.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 9441
Alternate Names
  • Cofactor required for Sp1 transcriptional activation subunit 7
  • mediator of RNA polymerase II transcription subunit 26
  • Activator-recruited cofactor 70 kDa component
  • cofactor required for Sp1 transcriptional activation, subunit 7 (70kD)
  • cofactor required for Sp1 transcriptional activation, subunit 7, 70kDa
  • CRSP7CRSP complex subunit 7
  • CRSP70ARC70
  • mediator complex subunit 26Transcriptional coactivator CRSP70

Diseases related to MED26

Discover more about diseases related to MED26.

Congenital Heart Defects
Nervousness
Transposition Of Great Vessels

Pathways for MED26

View related products by pathway and learn more about each of the pathways below.

Transposition
Gene Silencing

Bioinformatics Tool for MED26

Discover related pathways, diseases and genes to MED26. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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