Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
9441 |
| Alternate Names |
- Activator-recruited cofactor 70 kDa component
- Cofactor required for Sp1 transcriptional activation subunit 7
- cofactor required for Sp1 transcriptional activation, subunit 7 (70kD)
- cofactor required for Sp1 transcriptional activation, subunit 7, 70kDa
- CRSP70ARC70
- CRSP7CRSP complex subunit 7
- mediator complex subunit 26Transcriptional coactivator CRSP70
- mediator of RNA polymerase II transcription subunit 26
|
