MED26 Products

MED26 Antibody
MED26 Antibody
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
MED26 Antibody (2G10)
MED26 Antibody (2G10)
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
MED26 Antibody
MED26 Antibody
Species: Hu
Applications: ICC/IF
Host: Rabbit Polyclonal
MED26 293T Cell Transient Ove ...
MED26 293T Cell Transient Overexpr...
Species: Hu
Applications: WB
Recombinant Human MED26 GST ( ...
Recombinant Human MED26 GST (N-Ter...
Species: Hu
Applications: WB, ELISA, PA, PAGE, AP
Recombinant Human MED26 GST ( ...
Recombinant Human MED26 GST (N-Ter...
Species: Hu
Applications: WB, ELISA, PA, AP
MED26 Recombinant Protein Ant ...
MED26 Recombinant Protein Antigen
Species: Hu
Applications: AC


In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase. These complexes include CRSP (for cofactor required for Sp1 activation), which is required, in conjunction with TAFIIs, for transcriptional activation by Sp1. CRSP is ubiquitously expressed in various tissues and functions as a multimeric complex that consists of nine distinct subunits. Several members of the CRSP family share sequence similarity with multiple components of the yeast transcriptional mediator proteins, including CRSP150, which is related to yeast Rgr1, and CRSP70, which is similar to the elongation factor TFIIS. CRSP77 and CRSP150 are also related to proteins within the putative murine mediator complex, while CRSP130 and CRSP34 are largely unrelated to either murine or yeast proteins. CRSP subunits also associate with larger multimeric coactivaor complexes, including ARC/DRI, which binds directly to SREBP and nuclear hormone receptors to facilitate transcription, and with NAT, a polymerase II-interacting complex that represses activated transcription.


Entrez Human
Uniprot Human
Product By Gene ID 9441
Alternate Names
  • Cofactor required for Sp1 transcriptional activation subunit 7
  • mediator of RNA polymerase II transcription subunit 26
  • Activator-recruited cofactor 70 kDa component
  • cofactor required for Sp1 transcriptional activation, subunit 7 (70kD)
  • cofactor required for Sp1 transcriptional activation, subunit 7, 70kDa
  • CRSP7CRSP complex subunit 7
  • CRSP70ARC70
  • mediator complex subunit 26Transcriptional coactivator CRSP70

Diseases related to MED26

Discover more about diseases related to MED26.

Congenital Heart Defects
Transposition Of Great Vessels

Pathways for MED26

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Gene Silencing

Bioinformatics Tool for MED26

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