MED17 Products

Description

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

Bioinformatics

Entrez	234959 Mouse 9440 Human
Uniprot	AAH21101 Human AAH21101.1 Human NM_004268 Human Q9NVC6 Human
Product By Gene ID	9440
Alternate Names	Activator-recruited cofactor 77 kDa component Cofactor required for Sp1 transcriptional activation subunit 6 cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa CRSP6FLJ10812 CRSP77cofactor required for Sp1 transcriptional activation, subunit 6 (77kD) DRIP77 DRIP80ARC77 mediator complex subunit 17Vitamin D3 receptor-interacting protein complex 80 kDa component mediator of RNA polymerase II transcription subunit 17 Thyroid hormone receptor-associated protein complex 80 kDa component Transcriptional coactivator CRSP77 Trap80 TRAP80CRSP complex subunit 6

Research Areas for MED17

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Signal Transduction