MED14 Products

RNAi
MED14 RNAi
MED14 RNAi
H00009282-R01
Species: Hu

Description

The activation of gene transcription is a multi-step process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multi-subunit complexes e.g. thyroid hormone receptor (TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Product By Gene ID 9282
Alternate Names
  • ARC150
  • Trap170
  • Vitamin D3 receptor-interacting protein complex 150 kDa component
  • vitamin D receptor-interacting protein complex component DRIP150
  • Transcriptional coactivator CRSP150
  • transcriptional co-activator CRSP150
  • Thyroid hormone receptor-associated protein complex 170 kDa component
  • thyroid hormone receptor-associated protein complex component TRAP170
  • Cofactor required for Sp1 transcriptional activation subunit 2
  • mediator of RNA polymerase II transcription subunit 14
  • Activator-recruited cofactor 150 kDa component
  • human homolog of yeast RGR1
  • CSRP
  • cofactor required for Sp1 transcriptional activation, subunit 2 (150kD)
  • CRSP150
  • CXorf4MGC104513
  • CRSP2cofactor required for Sp1 transcriptional activation, subunit 2, 150kDa
  • RGR1RGR1 homolog
  • TRAP170hRGR1
  • EXLM1CRSP complex subunit 2
  • mediator complex subunit 14DRIP150

Research Areas for MED14

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Signal Transduction

PTMs for MED14

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Phosphorylation

Bioinformatics Tool for MED14

Discover related pathways, diseases and genes to MED14. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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