MDR1/ABCB1 Products

Antibodies
MDR1/ABCB1 Antibody (C219)
MDR1/ABCB1 Antibody (C219)
NB600-1036
Species: Hu, Mu, Rt, Ca, Pm
Applications: WB, B/N, ICC/IF, IHC, IHC-P, IP
Host: Mouse Monoclonal
MDR1/ABCB1 Antibody
MDR1/ABCB1 Antibody
NB100-80870
Species: Hu, Mu, Rt, Ca, Mk
Applications: WB, ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
MDR1/ABCB1 Antibody (1A7)
MDR1/ABCB1 Antibody (1A7)
Species: Hu
Applications: IHC
Host: Mouse monoclonal
Proteins
MDR1/ABCB1 Partial Recombinan ...
MDR1/ABCB1 Partial Recombinant Pro...
H00005243-Q01
Species: Hu
Applications: WB, ELISA, PA
MDR1/ABCB1 Recombinant Protei ...
MDR1/ABCB1 Recombinant Protein Ant...
NBP1-90291PEP
Species: Hu
Applications: AC
RNAi
MDR1/ABCB1 RNAi
MDR1/ABCB1 RNAi
H00005243-R02
Species: Hu

Description

MDR1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). MDR1 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. (provided by RefSeq)

Bioinformatics

Entrez Human
Mouse
Mouse
Rat
Uniprot Human
Human
Product By Gene ID 5243
Alternate Names
  • P-gp
  • EC 3.6.3
  • EC 3.6.3.44
  • IBD13
  • P-glycoprotein 1
  • CD243 antigen
  • colchicin sensitivity
  • ATP-binding cassette sub-family B member 1
  • GP170
  • multidrug resistance protein 1
  • CD243
  • doxorubicin resistance
  • ABC20
  • PGY1P-GP
  • MDR1MGC163296
  • CLCS
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1

Research Areas for MDR1/ABCB1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Membrane Trafficking and Chaperones

Bioinformatics Tool for MDR1/ABCB1

Discover related pathways, diseases and genes to MDR1/ABCB1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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